M-CSF/CSF1, Mouse, Recombinant
货号： PCK043
Price： ￥12880 ￥6280 ￥3480 ￥1180 ￥18880
产品信息
| 产品形态 | 粉末 |
| 产品规格 | 500μg / 100μg / 50μg / 10μg / 1mg |
| 别名 | Macrophage colony-stimulating factor 1;CSF-1;MCSF;Csf1;Csfm |
| 物种 | 小鼠 |
| 表达宿主 | Human Cells |
| 序列信息 | Lys33-Glu262 |
| 检索号 | P07141 |
| 分子量 | 26.0 kDa |
| 表观分子量 | 37-80kDa |
| 生物活性 | Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 0.04-0.2 ng/mL. |
| 纯度 | > 95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per 1 μg as determined by LAL test. |
| 储存条件 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
| 运输条件 | Ambient temperature or ice pack. |
| 有效期 | 12个月 |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 背景介绍 | Macrophage colony-stimulating factor 1 (M-csf) is a single-pass type I membrane Protein. It is a hematopoietic Growth Factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane Receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy. |
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Dexamethasone upregulates macrophage PIEZO1 via SGK1, suppressing inflammation and increasing ROS and apoptosis(2024)
期刊：BIOCHEMICAL PHARMACOLOGY
影响因子：5.300
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New-QiangGuYin-Containing Serum Inhibits Osteoclast-Derived Exosome Secretion and Down-Regulates Notum to Promote Osteoblast Differentiation(2024)
期刊：Advanced Biology
影响因子：3.200
引用产品： M-CSF/CSF1, Mouse, Recombinant, 青霉素-链霉素溶液（双抗），100×, 小鼠骨髓间充质干细胞完全培养基, 特级胎牛血清, RAW 264.7 细胞, 小鼠骨髓间充质干细胞, DMEM高糖 培养基 , 小鼠骨髓间充质干细胞成骨诱导分化培养基
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A self-assembled bilayer polypeptide-engineered hydrogel for spatiotemporal modulation of bactericidal and anti-inflammation process in osteomyelitis treatment(2022)
期刊：JOURNAL OF NANOBIOTECHNOLOGY
DOI：10.1186/s12951-022-01614-3
影响因子：9.429
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Q1:NFS-60细胞完培中的M-CSF因子，可以用PCK043这款吗
可以。
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Q2:官网的因子都是不含动物成分的么？
我们公司的因子都是重组的，是不含动物源成分的。
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Q3:这个重组蛋白如果我想加入细胞里，用哪个溶解呢 ？因为随产品附赠了一管pbs和一管无菌水
首次复融使用无菌水，复融后如果还需要进一步稀释的话，使用含海藻糖的PBS进行稀释。
识别码示意图
