Saos-2(人成骨肉瘤细胞)

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货号: CL-0202

Price: ¥1600 ¥1600

Size:
1×10^6Cells/T25 1×10^6Cells/Vial×2Vials

生长培养基: McCoy's 5A[PM150710]+15% FBS[164210]+1% P/S[PB180120]

产品信息

产品名称 Saos-2(人成骨肉瘤细胞)
别称 SAOS-2; Saos-2; SAOS 2; Saos 2; Saos2; SaOs2; SAOS2; Sarcoma OSteogenic-2; SaOS; SAOS
生长特性 贴壁细胞
细胞形态 上皮细胞样
冻存条件 冻存液:55% 基础培养基+40% FBS+5% DMSO
温度:液氮
培养方案A(默认) 生长培养基:McCoy's 5A[PM150710]+15% FBS[164210]+1% P/S[PB180120]
培养条件: 气相:空气,95%;CO₂,5%, 温度:37℃
培养方案B(可选) 生长培养基:
培养条件: 气相:, 温度:37℃
推荐传代比例 1:2-1:3
推荐换液频率 2-3次/周

参考资料(来源文献)

背景描述 Saos-2细胞是由J·Fogh和G·Trempe分离和鉴定的众多人肿瘤细胞系中的一种。该病人曾经多种药物治疗,包括RTG、methotrexate、adriamycin vincristine、cytoxan和aramycin-C。Saos-2细胞在免疫抑制小鼠中不致瘤,但在半固体培养基中形成集落。
年龄(性别) 11Y Female
组织来源 骨;骨肉瘤
细胞类型 肿瘤细胞
肿瘤类型 肉瘤细胞
生物安全等级 BSL-1
致瘤性 No, The cells were not tumorigenic in immunosuppressed mice, but did form colonies in semisolid medium.
受体表达情况 epidermal growth factor (EGF); transforming growth factor beta (Type 1 and Type 2)

STR位点信息

STR鉴定图

  • Single-Atom Cu Nanozyme-Loaded Bone Scaffolds for Ferroptosis-Synergized Mild Photothermal Therapy in Osteosarcoma Treatment(2024)

    作者:Zuyun Yan, Xin Wu, Wei Tan, Jinpeng Yan, Jun Zhou, Shijie Chen, Jinglei Miao, Jun Cheng, Cijun Shuai, Youwen Deng

    期刊:Advanced Healthcare Materials

    DOI:10.1002/adhm.202304595

    影响因子:10.0

    引用产品: Saos-2 细胞

  • Single-cell and spatial transcriptomics reveal metastasis mechanism and microenvironment remodeling of lymph node in osteosarcoma(2024)

    作者:Liu Yun, He Mingwei, Tang Haijun, Xie Tianyu, Lin Yunhua, Liu Shangyu, Liang Jiming, Li Feicui, Luo Kai, Yang Mingxiu, Teng Hongcai, Luo Xiaoting, He Juliang, Liao Shijie, Huang Qian, Feng Wenyu, Zhan Xinli, Wei Qingjun

    期刊:BMC Medicine

    DOI:10.1186/s12916-024-03319-w

    影响因子:9.3

    引用产品: hFOB 1.19 细胞, 143B 细胞, Saos-2 细胞

  • Multi-omics analysis reveals cuproptosis and mitochondria-based signature for assessing prognosis and immune landscape in osteosarcoma(2024)

    作者:Chenguang Jia, Mei Liu, Liming Yao, Fangchao Zhao, Shuren Liu, Zhuo Li, Yongtai Han

    期刊:Frontiers in Immunology

    DOI:10.3389/fimmu.2023.1280945

    影响因子:7.3

    引用产品: hFOB 1.19 细胞, HOS 细胞, Saos-2 细胞, 143B 细胞

  • SNRNP70 regulates the splicing of CD55 to promote osteosarcoma progression(2024)

    作者:Wenyue Li, Linzhu Wang, Wen Tian, Weihang Ji, Danyang Bing, Yan Wang, Bingqian Xu, Jiayue Feng, Peng Zhang, Haihai Liang, Yunyan Gu, Baofeng Yang

    期刊:JCI Insight

    DOI:10.1172/jci.insight.185269

    影响因子:6.3

    引用产品: MG-63 细胞, Saos-2 细胞, U-2 OS [U2OS] 细胞

  • CGREF1 modulates osteosarcoma proliferation by regulating the cell cycle through the Wnt/β-catenin signaling pathway(2024)

    作者:Wei Zicheng, Xia Kezhou, Liu Wenda, Huang Xinghan, Wei Zhun, Guo Weichun

    期刊:MOLECULAR MEDICINE

    DOI:10.1186/s10020-024-01038-9

    影响因子:6.0

    引用产品: Saos-2 细胞, U-2 OS [U2OS] 细胞, 143B 细胞, MG-63 细胞

  • Soy isoflavones induces mitophagy to inhibit the progression of osteosarcoma by blocking the AKT/mTOR signaling pathway(2024)

    作者:Zheng Ziang, Zhao Xinghan, Yuan Bo, Jiang Shan, Yan Rushan, Dong Xiaowei, Yao Qijun, Liang Haidong

    期刊:MOLECULAR MEDICINE

    DOI:10.1186/s10020-024-00778-y

    影响因子:5.7

    引用产品: U-2 OS [U2OS] 细胞, Saos-2 细胞, MG-63 细胞

  • Comprehensive investigation of tumor immune microenvironment and prognostic biomarkers in osteosarcoma through integrated bulk and single-cell transcriptomic analysis(2024)

    作者:Shi Shaoyan, Zhang Li, Guo Xiaohua

    期刊:Frontiers in Immunology

    DOI:10.3389/fimmu.2024.1424950

    影响因子:5.7

    引用产品: Saos-2 细胞, MG-63 细胞

  • Sirtuin 3-activated superoxide dismutase 2 mediates fluoride-induced osteoblastic differentiation in vitro and in vivo by down-regulating reactive oxygen species(2024)

    作者:Yang Liu, Li Qiao, Wang Sa, Ji Yi, Ma Xinbo, Qin Ming, Gao Yanhui, Yang Yanmei

    期刊:ARCHIVES OF TOXICOLOGY

    DOI:10.1007/s00204-024-03819-x

    影响因子:4.8

    引用产品: McCoy's 5A 培养基 , MG-63 细胞, Saos-2 细胞, MG-63细胞专用培养基

  • IMPC-based screening revealed that ROBO1 can regulate osteoporosis by inhibiting osteogenic differentiation(2024)

    作者:Zhang Xiangzheng, Wang Yike, Zheng Miao, Wei Qi, Zhang Ruizhi, Zhu Keyu, Zhai Qiaocheng, Xu Youjia

    期刊:Frontiers in Cell and Developmental Biology

    DOI:10.3389/fcell.2024.1450215

    影响因子:4.6

    引用产品: Saos-2 细胞, 小鼠骨髓间充质干细胞, MC3T3-E1 Subclone 14 细胞

  • CircPRMT5 promotes progression of osteosarcoma by recruiting CNBP to regulate the translation and stability of CDK6 mRNA(2024)

    作者:Yunlu Liu, Hongyan Jiang, Keli Hu, Hui Zou, Weiguo Zhang, Jiangtao Liu, Xiaofei Jian

    期刊:PLoS One

    DOI:10.1371/journal.pone.0298947

    影响因子:3.7

    引用产品: hFOB 1.19 细胞, Saos-2 细胞

  • Q1:为什么我看的文献里的细胞培养条件和你们官网的培养条件不一样呢?

    部分细胞是会出现多种培养条件的,我们公司优先选择引种来源的培养条件以及建系者所用培养条件,出现差异的原因是不同实验室在保藏过程中更改了细胞的培养条件,为了避免细胞突然更换培养条件后不适应,建议您优先使用厂家推荐的培养条件培养。

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