VEGF-A/VEGF121, Human, Recombinant
货号： PCK013
Price： ￥11880 ￥3480 ￥1180 ￥18880
产品信息
| 产品形态 | 粉末 |
| 产品规格 | 500μg / 50μg / 10μg / 1mg |
| 别名 | Vascular Endothelial Growth Factor A;VEGFA;VEGF-A;Vascular Permeability Factor;VPF;VEGF;VEGF121 |
| 物种 | 人 |
| 表达宿主 | E.coli |
| 序列信息 | Ala27-Arg147 |
| 检索号 | P15692-9 |
| 分子量 | 14.2 kDa |
| 表观分子量 | 16 kDa |
| 生物活性 | Immobilized Human VEGF 121 at 2 μg/mL (100 μL/well) can bind Human VEGFR2-Fc. The ED50 of Human VEGFR2-Fc is 13.04 ng/mL. |
| 纯度 | > 95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per 1 μg as determined by LAL test. |
| 储存条件 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
| 运输条件 | Ambient temperature or ice pack. |
| 有效期 | 12个月 |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 背景介绍 | Human VEGF121, also known as Vascular Endothelial Growth Factor A, VEGFA, Vascular Permeability Factor, VPF and VEGF, is a homodimeric, heparin-binding glyco Protein which belongs to the platelet-Derived Growth Factor (PDGF)/vascular Endothelial Growth Factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on Endothelial cells and has various effects, including mediating increased vascular Permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessels and Endothelial cell Growth, increasing microvascular Permeability, promoting cell migration and inhibiting apoptosis. Alternatively spliced transcript variants of VEGF-A encod either secreted or cell-associated isoforms. The lymphangiogenesis may be promoted by upregulation of VEGF121, which may in turn act in part via induction of VEGF-C. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 Receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor Growth. |
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Dissolvable microneedle-based wound dressing transdermally and continuously delivers anti-inflammatory and pro-angiogenic exosomes for diabetic wound treatment(2024)
期刊：Bioactive Materials
DOI：10.1016/j.bioactmat.2024.08.016
影响因子：18.000
引用产品： VEGF-A/VEGF121, Human, Recombinant, 青霉素-链霉素-两性霉素B溶液（100×）
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Q1:官网的因子都是不含动物成分的么？
我们公司的因子都是重组的，是不含动物源成分的。
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Q2:这个重组蛋白如果我想加入细胞里，用哪个溶解呢 ？因为随产品附赠了一管pbs和一管无菌水
首次复融使用无菌水，复融后如果还需要进一步稀释的话，使用含海藻糖的PBS进行稀释。
识别码示意图
