MV-4-11（人髓性单核细胞白血病细胞）

Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury(2024)

期刊：JOURNAL OF MEDICINAL CHEMISTRY

DOI：10.1021/acs.jmedchem.3c02441

影响因子：7.300

引用产品： RAW 264.7 细胞, MV-4-11 细胞

Dimethoxytolyl propylresorcinol induces apoptosis and mitophagy in human leukemia cells through the PI3K/AKT pathway(2024)

期刊：Journal of Cancer

DOI：10.7150/jca.89243

影响因子：3.900

引用产品： 特级胎牛血清, MV-4-11 细胞, U-87 MG 细胞

Targeting cytohesin-1 suppresses acute myeloid leukemia progression and overcomes resistance to ABT-199(2023)

期刊：ACTA PHARMACOLOGICA SINICA

DOI：10.1038/s41401-023-01142-2

影响因子：8.200

引用产品： MV-4-11 细胞

Design, synthesis, activity and molecular dynamics studies of 1,3,4-thiadiazole derivatives as selective allosteric inhibitors of SHP2 for the treatment of cancer(2023)

期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

DOI：10.1016/j.ejmech.2023.115585

影响因子：6.700

引用产品： MV-4-11 细胞, NCI-H358 细胞, A549 [A-549] 细胞, MDA-MB-468 细胞

Discovery of a high potent PIM kinase inhibitor for acute myeloid leukemia based on N-pyridinyl amide scaffold by optimizing the fragments toward to Lys67 and Asp128/Glu171(2023)

期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

DOI：10.1016/j.ejmech.2023.115514

影响因子：6.700

引用产品： MV-4-11 细胞

Oncogenic FLT3 internal tandem duplication activates E2F1 to regulate purine metabolism in acute myeloid leukaemia(2023)

期刊：BIOCHEMICAL PHARMACOLOGY

DOI：10.1016/j.bcp.2023.115458

影响因子：5.800

引用产品： MV-4-11 细胞, THP-1 细胞

Synthesis and bioactivity evaluation of ferrocene-based hydroxamic acids as selective histone deacetylase 6 inhibitors(2022)

期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

DOI：10.1016/j.ejmech.2022.115004

影响因子：7.100

引用产品： 22RV1 细胞, MM.1S 细胞, MV-4-11 细胞, JeKo-1 细胞, 4T1 细胞, DMEM高糖 培养基

The Translational Landscape Revealed the Sequential Treatment Containing ATRA plus PI3K/AKT Inhibitors as an Efficient Strategy for AML Therapy(2022)

期刊：Pharmaceutics

DOI：10.3390/pharmaceutics14112329

影响因子：6.500

引用产品： MV-4-11 细胞

Circ_KCNQ5 participates in the progression of childhood acute myeloid leukemia by enhancing the expression of RAB10 via binding to miR-622(2022)

期刊：Hematology

DOI：10.1080/16078454.2022.2056983

影响因子：1.900

引用产品： Kasumi-1 细胞, MV-4-11 细胞

DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation(2021)

期刊：Cell Reports

DOI：10.1016/j.celrep.2021.109739

影响因子：8.800

引用产品： RPMI-1640 培养基, IMDM 培养基, MV-4-11 细胞, THP-1 细胞