货号： CL-0865
Price： ￥1800 ￥1800
生长培养基： RPMI-1640[PM150110]+20% FBS[164210]+20 ng/mL testosterone+0.5% ITS-G（100×）[PB180429]+1% P/S[PB180120]
产品信息
| 产品名称 | BPH-1（人前列腺增生细胞） |
| 别称 | BPH1; Benign Prostatic Hyperplasia-1 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 |
冻存液：55% 基础培养基+40% FBS+5% DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:RPMI-1640[PM150110]+20% FBS[164210]+20 ng/mL testosterone+0.5% ITS-G（100×）[PB180429]+1% P/S[PB180120] 培养条件: 气相：空气，95%；CO₂，5%, 温度：37℃ |
| 培养方案B（可选） |
生长培养基: 培养条件: 气相：, 温度：37℃ |
| 推荐传代比例 | 1:3-1:5 |
| 推荐换液频率 | 2-3次/周 |
参考资料(来源文献)
| 背景描述 | prostate epithelial cells from a 68-year-old man with benign prostate hyperplasia; cells were immortalized with SV-40 large T-antigen; cells were described in the literature to express cytokeratins 8, 18, and 19 (but not 14) and to metabolize prostatic androgens. |
| 年龄（性别） | 68Y Male |
| 组织来源 | 前列腺 |
| 细胞类型 | 转化细胞系 |
| 生物安全等级 | BSL-1 |
STR位点信息
STR鉴定图
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Identification and functional activity of Nik related kinase (NRK) in benign hyperplastic prostate(2024)
作者：He Weixiang, Tian Zelin, Dong Bingchen, Cao Yitong, Hu Wei, Wu Peng, Yu Lei, Zhang Xinhua, Guo Shanshan
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-05048-3
影响因子：7.4
引用产品： BPH-1 细胞
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Y-27632 targeting ROCK1&2 modulates cell growth, fibrosis and epithelial-mesenchymal transition in hyperplastic prostate by inhibiting β-catenin pathway(2024)
作者：Shan Shidong, Su Min, Wang Hejin, Guo Feng, Li Yan, Zhou Yongying, Liu Huan, Du Lu, Zhang Junchao, Qiu Jizhang, DiSanto Michael E., Guo Yuming, Zhang Xinhua
期刊：Molecular Biomedicine
DOI：10.1186/s43556-024-00216-9
影响因子：6.3
引用产品： BPH-1 细胞
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Epigenetic-related Gene-based Prognostic Model Construction and Validation in Prostate Adenocarcinoma(2024)
作者：Youyou Li, Chao Li, Longxiang Wu, Jiaren Li, Yu Gan, Shuo Tan, Lei Zhou, Wei Xiong, Liang Zhou, Cheng Li, Jiahao Liu, Dingwen Liu, Yichuan Wang, Yunlong Fu, Kun Yao, Long Wang
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e30941
影响因子：4.0
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Identification of RBM15 as a prognostic biomarker in prostate cancer involving the regulation of prognostic m6A-related lncRNAs(2024)
作者：Hu Bintao, Lin Dongxu, Liu Zhicheng, Chen Ruibao, Liu Jihong, Wu Yue, Wang Tao
期刊：EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI：10.1186/s40001-024-02000-5
影响因子：2.8
引用产品： BPH-1 细胞, C4-2 细胞, PC-3 细胞, RWPE-1 细胞, DU 145 细胞, LNCaP clone FGC 细胞, 22RV1 细胞
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ARPC1A correlates with poor prognosis in prostate cancer and is up-regulated by glutamine metabolism to promote tumor cell migration, invasion and cytoskeletal changes(2023)
作者：Chen Ye-Hui, Chen Hang, Lin Ting-Ting, Zhu Jun-Ming, Chen Jia-Yin, Dong Ru-Nan, Chen Shao-Hao, Lin Fei, Ke Zhi-Bin, Huang Jin-Bei, Wei Yong, Zheng Qing-Shui, Xue Xue-Yi, Xu Ning
期刊：Cell and Bioscience
DOI：10.1186/s13578-023-00985-w
影响因子：7.5
引用产品： BPH-1 细胞
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Mechanism of RhoA regulating benign prostatic hyperplasia: RhoA-ROCK-β-catenin signaling axis and static & dynamic dual roles(2023)
作者：Shan Shidong, Su Min, Li Yan, Wang Zhen, Liu Daoquan, Zhou Yongying, Fu Xun, Yang Shu, Zhang Junchao, Qiu Jizhang, Liu Huan, Zeng Guang, Chen Ping, Wang Xinghuan, DiSanto Michael E., Guo Yuming, Zhang Xinhua
期刊：MOLECULAR MEDICINE
DOI：10.1186/s10020-023-00734-2
影响因子：5.7
引用产品： BPH-1 细胞
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STEAP4 modulates cell proliferation and oxidative stress in benign prostatic hyperplasia(2023)
作者：Jiang Liu, Wei Zhou, Liang Yang, Yan Li, Jizhang Qiu, Xun Fu, Pengfei Ren, Feng Guo, Yongying Zhou, Jianmin Liu, Ping Chen, Michael E. DiSanto, Xinhua Zhang
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2023.110933
影响因子：4.8
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Changes in the Expression and Functional Activities of C-X-C Motif Chemokine Ligand 13 (CXCL13) in Hyperplastic Prostate(2022)
作者：Daoquan Liu, Mingzhou Li, Xun Fu, Shu Yang, Zhen Wang, Jianmin Liu, Yan Li, Yongying Zhou, Pengfei Ren, Yuhang Guo, Xinghuan Wang, Michael E. DiSanto, Ping Chen, Xinhua Zhang
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子：6.2
引用产品： BPH-1 细胞
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Q1:为什么我看的文献里的细胞培养条件和你们官网的培养条件不一样呢？
部分细胞是会出现多种培养条件的，我们公司优先选择引种来源的培养条件以及建系者所用培养条件，出现差异的原因是不同实验室在保藏过程中更改了细胞的培养条件，为了避免细胞突然更换培养条件后不适应，建议您优先使用厂家推荐的培养条件培养。
识别码示意图
