货号： CL-0765
Price： ￥1800 ￥1800
生长培养基： RPMI-1640[PM150110]+10% FBS[164210]+1% P/S[PB180120]
产品信息
| 产品名称 | HTR-8-Svneo（人绒毛膜滋养层细胞） |
| 别称 | HTR-8/SV neo; HTR-8/SV-neo; HTR8/SVneo; HTR8svn |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 |
冻存液：55% 基础培养基+40% FBS+5% DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:RPMI-1640[PM150110]+10% FBS[164210]+1% P/S[PB180120] 培养条件: 气相：空气，95%；CO₂，5%, 温度：37℃ |
| 培养方案B（可选） |
生长培养基: 培养条件: 气相：, 温度：37℃ |
| 推荐传代比例 | 1:2-1:3 |
| 推荐换液频率 | 2-3次/周 |
参考资料(来源文献)
| 背景描述 | The HTR-8-Svneo cell line was derived by transfecting the cells that grew out of chorinic villi explants of human first-trimester placenta with the gene encoding for simian virus 40 large T antigen. |
| 年龄（性别） | 6-12FW Sex unspecified |
| 组织来源 | 胎盘 |
| 细胞类型 | 转化细胞系 |
| 生物安全等级 | BSL-1 |
| 致瘤性 | No (tested in soft agar and nude mice). |
STR位点信息
STR鉴定图
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Mitochondrial Mayhem: How cigarette smoke induces placental dysfunction through MMS19 degradation(2025)
作者：Pei Zhou, Feng Jin, Shenshen Yao, Ben Sun, Ni Sun, Hongbo Guan, Xiaomei Liu
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2025.117728
影响因子：6.2
引用产品： HTR-8-Svneo 细胞, RPMI-1640 培养基, 特级胎牛血清
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Trophoblast-derived miR-410-5p induces M2 macrophage polarization and mediates immunotolerance at the fetal-maternal interface by targeting the STAT1 signaling pathway(2024)
作者：Yang Jing, Li Longfei, Wang Linlin, Chen Ruizhi, Yang Xiaobing, Wu Juanhua, Feng Gang, Ding Jinli, Diao Lianghui, Chen Jiao, Yang Jing
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-023-04831-y
影响因子：7.4
引用产品： HTR-8-Svneo 细胞, JEG-3 细胞, THP-1 细胞, RAW 264.7 细胞
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MLL1 promotes placental trophoblast ferroptosis and aggravates preeclampsia symptoms through epigenetic regulation of RBM15/TRIM72/ADAM9 axis(2024)
作者：Li Lingling, He Haining, Zheng Zhenrong, Zhao Xiaolan
期刊：Biology Direct
DOI：10.1186/s13062-024-00572-0
影响因子：5.7
引用产品： HTR-8-Svneo 细胞
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Effect of exercise during pregnancy on offspring development through ameliorating high glucose and hypoxia in gestational diabetes mellitus(2024)
作者：Yi-Bo Tang, Le-Sha Wang, Yi-Hui Wu, Li-Xia Zhang, Lu-Yao Hu, Qi Wu, Meng-Lin Zhou, Zhao-Xia Liang
期刊：World Journal of Diabetes
影响因子：4.2
引用产品： HTR-8-Svneo 细胞, RPMI-1640 培养基
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Inhibition of the endoplasmic reticulum stress-associated IRE-1 pathway alleviates preterm birth(2024)
作者：Liyin Qiu, Hui Liu, Shali Chen, Yiting Wu, Jianying Yan
期刊：AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
影响因子：3.6
引用产品： HTR-8-Svneo 细胞
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NANOG regulate the JAK/STAT3 pathway to promote trophoblast cell migration and epithelial-mesenchymal transition (EMT) in hypertensive disorders of pregnancy (HDP) through protein interaction with CDK1(2024)
作者：Jing Ma, Mingchang Liu, Zhuo Chen, Shiyang Liu, Huijuan Yang, Mengjia Duan
期刊：AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
影响因子：3.6
引用产品： HTR-8-Svneo 细胞
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LIM homeobox 1 (LHX1) induces endoplasmic reticulum stress and promotes preterm birth(2024)
作者：Liyin Qiu, Zhaozhen Liu, Shouzhen Chen, Yiting Wu, Jianying Yan
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e32457
影响因子：3.4
引用产品： HTR-8-Svneo 细胞
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SIRT5 suppresses the trophoblast cell proliferation, invasion, and migration to promote preeclampsia via desuccinylating HOXB3(2024)
作者：Ruan Jianbing, Zheng Jiacui, Zhang Xue, Chen Zhancui, Sun Yanqing, Jia Xueqin
期刊：JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
DOI：10.1007/s10815-024-03223-5
影响因子：3.2
引用产品： 青霉素-链霉素溶液（双抗），100×, HTR-8-Svneo 细胞, RPMI-1640 完全培养基（含10% FBS）
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Mechanisms of YAP1-mediated trophoblast ferroptosis in recurrent pregnancy loss(2024)
作者：Chen Liping, Dai Fangfang, Huang Yanjie, Chen Jing, Li Zhidian, Liu Hua, Cheng Yanxiang
期刊：JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
DOI：10.1007/s10815-024-03096-8
影响因子：3.1
引用产品： HTR-8-Svneo 细胞, JAR 细胞
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Establishment of a placental lncRNA-mRNA expression network for early-onset preeclampsia(2024)
作者：Chen Ya, Zhang Ying, Xie Siyu, Zhou Xiangdong, Zhu Lina, Cao Yunxia
期刊：BMC Pregnancy and Childbirth
DOI：10.1186/s12884-024-06481-4
影响因子：3.1
引用产品： HTR-8-Svneo 细胞
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Q1:为什么我看的文献里的细胞培养条件和你们官网的培养条件不一样呢？
部分细胞是会出现多种培养条件的，我们公司优先选择引种来源的培养条件以及建系者所用培养条件，出现差异的原因是不同实验室在保藏过程中更改了细胞的培养条件，为了避免细胞突然更换培养条件后不适应，建议您优先使用厂家推荐的培养条件培养。
识别码示意图
