货号： CL-0050
Price： ￥1600 ￥1600
生长培养基： MEM（含NEAA）[PM150410]+20%FBS[164210]+1%P/S[PB180120]
产品信息
| 产品名称 | Caco-2（人结直肠腺癌细胞） |
| 别称 | CaCo-2; CACO-2; Caco 2; CACO 2; CACO2; CaCo2; CaCO2; Caco2; Caco-2/ATCC |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 |
冻存液：55% 基础培养基+40% FBS+5% DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:MEM（含NEAA）[PM150410]+20%FBS[164210]+1%P/S[PB180120] 培养条件: 气相：空气，95%；CO₂，5%, 温度：37℃ |
| 培养方案B（可选） |
生长培养基: 培养条件: 气相：, 温度：37℃ |
| 推荐传代比例 | 1:3-1:6 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 |
|
参考资料(来源文献)
| 背景描述 | Caco-2细胞分离自直肠原位癌；当长到满时，Caco-2细胞表现出特征性的肠上皮细胞分化。Caco-2细胞表达维甲酸结合蛋白I和维甲酸结合蛋白Ⅱ，并呈角质蛋白阳性。 |
| 年龄（性别） | 72Y Male |
| 组织来源 | 结肠，结直肠腺癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肠癌细胞 |
| 生物安全等级 | BSL-1 |
| 致瘤性 | Yes, in nude mice; forms moderately well differentiated adenocarcinoma consistent with colonic primary (grade II). |
| 受体表达情况 | This cell line expressed heat stable enterotoxin (Sta, E. coli) and epidermal growth factor (EGF). |
STR位点信息
STR鉴定图
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Sulfobetaine modification of poly (D, L-lactide-co-glycolic acid) nanoparticles enhances mucus permeability and improves bioavailability of orally delivered liraglutide(2024)
作者：Zhenyu Zhao, Ruihuan Ding, Yumei Wang, Ranran Yuan, Houqian Zhang, Tianyang Li, Wei Zheng, Entao Chen, Aiping Wang, Yanan Shi
期刊：JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
DOI：10.1016/j.jddst.2024.105437
影响因子：5.0
引用产品： Caco-2 细胞, 特级胎牛血清, DMEM高糖 培养基
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Icariside II relieves radiation enteritis by regulating PINK/Parkin-mediated mitophagy(2024)
作者：Shuangyan He, Chengqiu Yan, Zhuo Wang, Yinhui Mao, Kunjian Liu, Juntao Sun, Yueyue Zang, Mingxing Wang, Guofeng Li, Yong Yang
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.113861
影响因子：4.8
引用产品： Caco-2 细胞
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Ghrelin alleviates intestinal ischemia–reperfusion injury by activating the GHSR-1α/Sirt1/FOXO1 pathway(2024)
作者：Shi-shi Liao, Le-le Zhang, Yi-guo Zhang, Jie Luo, Tulanisa Kadier, Ke Ding, Rong Chen, Qing-tao Meng
期刊：FASEB JOURNAL
影响因子：4.8
引用产品： Caco-2 细胞
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Camellia vietnamensis Huang. oil decreases inflammation and oxidative stress on pre-clinical models of ulcerative colitis(2024)
作者：Zhu Zhu, Yuehao Song, Li Zhang, Yiwen Guo, Yiyi Qian, Xiaoyu He, Ruijie Liu, Ming Chang, Xingguo Wang
期刊：Food Bioscience
DOI：10.1016/j.fbio.2024.105575
影响因子：4.8
引用产品： Caco-2 细胞
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Inhibitory mechanism of theaflavins on intestinal fluoride transport: A new insight from network pharmacology integrated transcriptomic analysis(2024)
作者：Jiasheng Huang, Zhendong Lei, Yueqin Fan, Zhi Yu, Dejiang Ni, Yuqiong Chen
期刊：Food Bioscience
DOI：10.1016/j.fbio.2024.105623
影响因子：4.8
引用产品： Caco-2 细胞
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Deer Skin Collagen Peptides Bound to Calcium: In Vitro Gastrointestinal Simulation of Digestion, Cellular Uptake and Analysis of Antioxidant Activity(2024)
作者：Rui Du, Li Sun, Jinze Liu, Fusheng Gao, Xiangjuan Guo, Meiling Shi, Pengli Guo, Weijia Chen, Ying Zong, Jianan Geng, Yan Zhao, Zhongmei He
期刊：Nutrients
影响因子：4.8
引用产品： Caco-2 细胞
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Novel angiotensin-converting enzyme inhibitory peptides derived from tuna (Thunnus maccoyii): the integration of computer tools with in vitro experiments(2024)
作者：Shu Wang, Lu Zhang, Hui Wang, Xiongchen Wu, Zongca Tu
期刊：Food Bioscience
DOI：10.1016/j.fbio.2024.105509
影响因子：4.8
引用产品： Caco-2 细胞
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Phosvitin phosphopeptides and peptides-calcium chelate promote calcium deposition in a three-cell co-culture system by modulating the OPG/RANKL/RANK signaling pathway(2024)
作者：Jiaojiao Chen, Songming Li, Mahmoud Abou-Elsoud, Wei Liu, Rui Cui, Zuyue Li, Dewei Shu, Zhaoxia Cai, Xi Huang
期刊：Food Bioscience
DOI：10.1016/j.fbio.2024.105065
影响因子：4.8
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Effect of Perilla frutescens polyphenols against tight junction alterations and intestinal inflammation: A Caco-2/macrophage co-culture model-based study integrated with network pharmacology(2024)
作者：Anqi Hu, Yuhui Ye, Binsong Han, Xiaoai Zhu, Feng Xue, Lifei Yang, Cunzheng Zhang
期刊：Food Bioscience
DOI：10.1016/j.fbio.2024.105459
影响因子：4.8
引用产品： Caco-2 细胞, RAW 264.7 细胞
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Identification and in silico screening of Novel Angiotensin-Converting Enzyme Inhibitory Peptides from Pacific saury: Interaction mechanism, Network pharmacology, Stability, Caco-2 monolayer transport(2024)
作者：Shu Wang, Hui Wang, Lu Zhang, Tianxin Ma, Zongcai Tu
期刊：Food Bioscience
DOI：10.1016/j.fbio.2024.104576
影响因子：4.8
引用产品： Caco-2 细胞, EA.hy926 细胞
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Q1:为什么我看的文献里的细胞培养条件和你们官网的培养条件不一样呢？
部分细胞是会出现多种培养条件的，我们公司优先选择引种来源的培养条件以及建系者所用培养条件，出现差异的原因是不同实验室在保藏过程中更改了细胞的培养条件，为了避免细胞突然更换培养条件后不适应，建议您优先使用厂家推荐的培养条件培养。
识别码示意图
