LX-2（人肝星形细胞）

Muscle-derived small extracellular vesicles induce liver fibrosis during overtraining(2025)

作者：Ya Liu, Rui Zhou, Yifan Guo, Biao Hu, Lingqi Xie, Yuze An, Jie Wen, Zheyu Liu, Min Zhou, Weihong Kuang, Yao Xiao, Min Wang, Genqing Xie, Haiyan Zhou, Renbin Lu, Hui Peng, Yan Huang

期刊：Cell Metabolism

DOI：10.1016/j.cmet.2024.12.005

影响因子：27.7

引用产品： 青霉素-链霉素溶液（双抗），100×, C2C12 细胞, LX-2 细胞, Hepa 1-6 细胞

Stromal architecture and fibroblast subpopulations with opposing effects on outcomes in hepatocellular carcinoma(2025)

作者：Cheng Yifei, Chen Xiaofang, Feng Li, Yang Zhicheng, Xiao Liyun, Xiang Bin, Wang Xiaodong, Liu Dongbin, Lin Penghui, Shi Jieyi, Song Guohe, Qian Wulei, Zhang Boan, Xu Yanan, Gao Zheng, Chen Lv, Wu Yingcheng, Ma Jiaqiang, Lin Youpei, Zhao Haichao, Peng Lihua, Mao Xuebin, Liu Yang, Hou Hao, Yang Mingyu, Ji Yuan, Wang Xiaoying, Zhou Jian, Xu Xun, Liu Xiyang, Wei Wu, Zhang Xiaoming, Gao Qiang, Zhou Hu, Sun Yidi, Wu Kui, Fan Jia

期刊：Cell Discovery

DOI：10.1038/s41421-024-00747-z

影响因子：13.0

引用产品： LX-2 细胞

The natural product-derived JM-9 alleviates high-fat diet-induced fatty liver in mice by targeting MD2(2025)

作者：Leiming Jin, Yaqian Cui, Qianhui Zhang, Yongqiang Xiong, Xiangsheng Zheng, Jiaxi Ye, Anqi Zhang, Zhongxiang Xiao, Zaishou Zhuang, Guang Liang, Xiang Hu, Wu Luo, Weiwei Zhu

期刊：INTERNATIONAL IMMUNOPHARMACOLOGY

DOI：10.1016/j.intimp.2025.114053

影响因子：4.8

引用产品： LX-2 细胞

Pulling the Rug Out from Under: Biomechanical Microenvironment Remodeling for Induction of Hepatic Stellate Cell Quiescence(2024)

作者：Haobo Wang, Qing You, Bei Kang, Huaqing Jing, Zhiyuan Shi, Sona Krizkova, Zbynek Heger, Vojtech Adam, Xiaoyuan Chen, Nan Li

期刊：ADVANCED MATERIALS

DOI：10.1002/adma.202406590

影响因子：27.4

引用产品： 特级胎牛血清, LX-2 细胞

An all-in-one tetrazine reagent for cysteine-selective labeling and bioorthogonal activable prodrug construction(2024)

作者：He Xinyu, Li Jie, Liang Xinxin, Mao Wuyu, Deng Xinglong, Qin Meng, Su Hao, Wu Haoxing

期刊：Nature Communications

DOI：10.1038/s41467-024-47188-6

影响因子：16.6

引用产品： SK-OV-3 细胞, MCF7 [MCF-7] 细胞, MDA-MB-231 细胞, U-87 MG 细胞, LX-2 细胞, Hep G2 细胞, B16-F10 细胞

RNA nanotherapeutics with fibrosis overexpression and retention for MASH treatment(2024)

作者：Shan Xinzhu, Zhao Zhiqiang, Lai Pingping, Liu Yuxiu, Li Buyao, Ke Yubin, Jiang Hanqiu, Zhou Yilong, Li Wenzhe, Wang Qian, Qin Pengxia, Xue Yizhe, Zhang Zihan, Wei Chenlong, Ma Bin, Liu Wei, Luo Cong, Lu Xueguang, Lin Jiaqi, Shu Li, Jie Yin, Xian Xunde, Delcassian Derfogail, Ge Yifan, Miao Lei

期刊：Nature Communications

DOI：10.1038/s41467-024-51571-8

影响因子：14.7

引用产品： THP-1 细胞, RAW 264.7 细胞, NIH/3T3 细胞, LX-2 细胞, 特级胎牛血清

FGF19-Activated Hepatic Stellate Cells Release ANGPTL4 that Promotes Colorectal Cancer Liver Metastasis(2024)

作者：Xueying Fan, Baoting Li, Fan Zhang, Meng Liu, Hiu-Yee Kwan, Zhongqiu Liu, Tao Su

期刊：Advanced Science

DOI：10.1002/advs.202413525

影响因子：14.3

引用产品： SW620 细胞, LX-2 细胞

Cancer Cell-Derived Exosomal miR-500a-3p Modulates Hepatic Stellate Cell Activation and the Immunosuppressive Microenvironment(2024)

作者：Yu Zhang, Xin Li, Huiyan Chen, Jiawei Li, Xiaohuan Guo, Yilin Fang, Linjie Chen, Kaiqiang Li, Yi Zhang, Fei Kong, Aodong Chen, Jianxin Lyu, Wei Zhang, Zhen Wang

期刊：Advanced Science

DOI：10.1002/advs.202404089

影响因子：14.3

引用产品： HuH-7 细胞, LX-2 细胞, SNU-387 细胞

MafG/MYH9-LCN2 axis promotes liver fibrosis through inhibiting ferroptosis of hepatic stellate cells(2024)

作者：Deng Yalan, Lu Liqing, Zhu Dandan, Zhang Huajun, Fu Ying, Tan Yuying, Tan Xuemei, Guo Ming, Zhang Ye, Yang Heping, Yang Bing, Liu Ting, Chen Yongheng

期刊：CELL DEATH AND DIFFERENTIATION

DOI：10.1038/s41418-024-01322-5

影响因子：13.7

引用产品： LX-2 细胞, HSC-T6 细胞

Impact of fine particulate matter on liver injury: evidence from human, mice and cells(2024)

作者：Yalan Xiao, Jialu Hu, Renjie Chen, Yanyi Xu, Bin Pan, Ya Gao, Yiran Deng, Wenshu Li, Haidong Kan, She Chen

期刊：JOURNAL OF HAZARDOUS MATERIALS

DOI：10.1016/j.jhazmat.2024.133958

影响因子：13.6

引用产品： LX-2 细胞