货号： CL-0480
Price： ￥1000 ￥1000
生长培养基： RPMI-1640[PM150110]+10% FBS[164210]+1% P/S[PB180120]
产品信息
| 产品名称 | PC-12 (Low differentiation)（大鼠肾上腺嗜铬细胞瘤细胞（低分化）） |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 多角形 |
| 冻存条件 |
冻存液：55% 基础培养基+40% FBS+5% DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:RPMI-1640[PM150110]+10% FBS[164210]+1% P/S[PB180120] 培养条件: 气相：空气，95%；CO₂，5%, 温度：37℃ |
| 培养方案B（可选） |
生长培养基: 培养条件: 气相：, 温度：37℃ |
| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 |
|
参考资料(来源文献)
| 背景描述 | PC-12(Low differentiation)细胞是来自能移植的雄性大鼠肾上腺嗜铬细胞瘤。PC-12(Low differentiation)细胞表达神经生长因子（NGF）受体，NGF可诱导产生神经表型。PC-12(Low differentiation)细胞不合成肾上腺素。 |
| 年龄（性别） | Male |
| 组织来源 | 肾上腺嗜铬细胞瘤 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 嗜铬细胞瘤细胞 |
STR位点信息
STR鉴定图
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Neuroprotective methylsuccinic acid and enoic acid derivatives from the fungus Xylaria longipes(2023)
作者：Jing Li, Yu-Fen Tan, Si-Qian Zhou, Shao Liu, Wen-Xuan Wang, Yue-Ping Jiang, Hong-Ping Long, Ji-Kai Liu
期刊：PHYTOCHEMISTRY
DOI：10.1016/j.phytochem.2023.113652
影响因子：3.8
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Integrated insight into the molecular mechanisms of selenium-modulated, MPP+-induced cytotoxicity in a Parkinson’s disease model(2023)
作者：Wen Liu, Feiyang Zhang, Wu Liang, Kaixin Huang, Chenguang Jia, Jie Zhang, Xiang Li, Wei Wei, Rui Gong, Jincao Chen
期刊：JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
DOI：10.1016/j.jtemb.2023.127208
影响因子：3.5
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Doping Ag2S quantum dots with Pb yields significantly enhanced in vivo fluorescence imaging in the NIR-II window and comparable toxic effects(2023)
作者：Qingyuan Cheng, Liman Li, Mingxia Yu
期刊：NEW JOURNAL OF CHEMISTRY
影响因子：3.3
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Puerarin reduces cell damage from cerebral ischemia-reperfusion by inhibiting ferroptosis(2023)
作者：Changxuan Li, Yu Liu
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2023.149324
影响因子：3.1
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METTL3 silenced inhibited the ferroptosis development via regulating the TFRC levels in the Intracerebral hemorrhage progression(2023)
作者：Liu Zhang, Xiangyu Wang, Wenqiang Che, Shuoming Zhou, Yongjian Feng
期刊：BRAIN RESEARCH
DOI：10.1016/j.brainres.2023.148373
影响因子：2.9
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Umbilical mesenchymal stem cell-derived exosomes promote spinal cord functional recovery through the miR-146b/TLR4 -mediated NF-κB p65 signaling pathway in rats(2023)
作者：Xiujuan Wang, Ying Yang, Wei Li, MingYuan Hao, YongSheng Xu
期刊：Biochemistry and Biophysics Reports
DOI：10.1016/j.bbrep.2023.101497
影响因子：2.7
引用产品： 人脐带间充质干细胞, PC-12 (Undifferentiated) 细胞
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STIM2 Suppression Blocks Glial Activation to Alleviate Brain Ischemia Reperfusion Injury via Inhibition of Inflammation and Pyroptosis(2023)
作者：Ye Xihong, Chen Qinyi, Gong Xingrui, Zhou Chunli, Yuan Tian, Wang Xue, Hong Lin, Zhang Jianfeng, Song Hua
期刊：MOLECULAR BIOTECHNOLOGY
DOI：10.1007/s12033-023-00823-x
影响因子：2.6
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Bone marrow mesenchymal stem cell-derived exosomal miR-193b-5p reduces pyroptosis after ischemic stroke by targeting AIM2(2023)
作者：Yingju Wang, Hongping Chen, Xuehui Fan, Chen Xu, Meng Li, Hongxue Sun, Jihe Song, Feihong Jia, Wan Wei, Fangchao Jiang, Guozhong Li, Di Zhong
期刊：Journal of Stroke & Cerebrovascular Diseases
DOI：10.1016/j.jstrokecerebrovasdis.2023.107235
影响因子：2.5
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Two pairs of new isobenzofuranone enantiomers from a soil-derived fungus Penicillium canescens DWS225(2023)
作者：Jing Wang, Xiao-Qian Wu, Ji-Song Mo, Yu-Fen Tan, Hong-Ping Long, Si-Qian Zhou, Shao Liu, Jing Li, Wen-Xuan Wang
期刊：NATURAL PRODUCT RESEARCH
DOI：10.1080/14786419.2023.2198712
影响因子：2.2
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Combining a Density Gradient of Biomacromolecular Nanoparticles with Biological Effectors in an Electrospun Fiber-Based Nerve Guidance Conduit to Promote Peripheral Nerve Repair(2022)
作者：Binghui Jin, Yiling Yu, Chenghao Lou, Xiaodi Zhang, Bowen Gong, Jinghao Chen, Xiangxiang Chen, Zihan Zhou, Liqun Zhang, Jian Xiao, Jiajia Xue
期刊：Advanced Science
影响因子：17.5
引用产品： PC-12 (Undifferentiated) 细胞, 多聚-L-赖氨酸溶液 (10×), PC-12 (Undifferentiated)细胞专用培养基
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Q1:为什么我看的文献里的细胞培养条件和你们官网的培养条件不一样呢？
部分细胞是会出现多种培养条件的，我们公司优先选择引种来源的培养条件以及建系者所用培养条件，出现差异的原因是不同实验室在保藏过程中更改了细胞的培养条件，为了避免细胞突然更换培养条件后不适应，建议您优先使用厂家推荐的培养条件培养。
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