货号： CL-0050
Price： ￥1600 ￥1600
生长培养基： MEM（含NEAA）[PM150410]+20%FBS[164210]+1%P/S[PB180120]
产品信息
| 产品名称 | Caco-2（人结直肠腺癌细胞） |
| 别称 | CaCo-2; CACO-2; Caco 2; CACO 2; CACO2; CaCo2; CaCO2; Caco2; Caco-2/ATCC |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 |
冻存液：55% 基础培养基+40% FBS+5% DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:MEM（含NEAA）[PM150410]+20%FBS[164210]+1%P/S[PB180120] 培养条件: 气相：空气，95%；CO₂，5%, 温度：37℃ |
| 培养方案B（可选） |
生长培养基: 培养条件: 气相：, 温度：37℃ |
| 推荐传代比例 | 1:3-1:6 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 |
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参考资料(来源文献)
| 背景描述 | Caco-2细胞分离自直肠原位癌；当长到满时，Caco-2细胞表现出特征性的肠上皮细胞分化。Caco-2细胞表达维甲酸结合蛋白I和维甲酸结合蛋白Ⅱ，并呈角质蛋白阳性。 |
| 年龄（性别） | 72Y Male |
| 组织来源 | 结肠，结直肠腺癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肠癌细胞 |
| 生物安全等级 | BSL-1 |
| 致瘤性 | Yes, in nude mice; forms moderately well differentiated adenocarcinoma consistent with colonic primary (grade II). |
| 受体表达情况 | This cell line expressed heat stable enterotoxin (Sta, E. coli) and epidermal growth factor (EGF). |
STR位点信息
STR鉴定图
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Lutein–stachyose (LS) amphiphilic oligosaccharide derivatives improve the oral bioavailability of lutein(2023)
作者：Yuanyuan Li, Bingxue Liu, Xiaoxue Zhang, Yanjie Liu, Siying Wang, Shujun Li, Xiuhua Zhao
期刊：FOOD CHEMISTRY
DOI：10.1016/j.foodchem.2023.136032
影响因子：8.8
引用产品： Caco-2 细胞
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A novel calcium-binding peptide from bovine bone collagen hydrolysate and chelation mechanism and calcium absorption activity of peptide-calcium chelate(2023)
作者：Liwei Qi, Hongru Zhang, Yujie Guo, Chunhui Zhang, Yang Xu
期刊：FOOD CHEMISTRY
DOI：10.1016/j.foodchem.2023.135387
影响因子：8.8
引用产品： Caco-2 细胞
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Chitosan-based oral nanoparticles as an efficient platform for kidney-targeted drug delivery in the treatment of renal fibrosis(2023)
作者：Qian Zhang, Ying Li, Shuai Wang, Donghao Gu, Cuihua Zhang, Shihao Xu, Xiaoli Fang, Chenyang Li, Haiqiang Wu, Wei Xiong
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2023.128315
影响因子：8.2
引用产品： Caco-2 细胞
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Construction and functional evaluation of oral long-acting insulin hydrogel microparticles based on physical and chemical double crosslinking(2023)
作者：ShengQin Chen, QingYa Miao, Yang Liu, Qiao Xiao, YuKai Lin, Yu Yang, FengBiao Guo
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2023.126915
影响因子：8.2
引用产品： Caco-2 细胞, Caco-2细胞专用培养基
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Identification of novel angiotensin converting enzyme (ACE) inhibitory peptides from Pacific saury: In vivo antihypertensive effect and transport route(2023)
作者：Shu Wang, Lu Zhang, Hui Wang, Zizi Hu, Xing Xie, Haiqi Chen, Zongcai Tu
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2023.127196
影响因子：8.2
引用产品： Caco-2 细胞
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Encapsulation of lycopene into electrospun nanofibers from whey protein isolate-Tricholoma lobayense polysaccharide complex stabilized emulsions: Structural characterization, storage stability, in vitro release, and cellular evaluation(2023)
作者：Lei Chen, Ming Xiang, Fen Wu, Yun Jiang, Qingxi Wu, Wenna Zhang, Wenqiang Guo, Bolin Cai, Li Liang, Songnan Li, Yan Chen, Xianfeng Du
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2023.123993
影响因子：8.2
引用产品： Caco-2 细胞
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(–)-Syringaresinol Attenuates Ulcerative Colitis By Improving Intestinal Epithelial Barrier Function And Inhibiting Inflammatory Responses(2023)
作者：Yunhe Liu, Junzhe Wu, Luying Tan, Zhuoqiao Li, Peng Gao, Shanmei He, Qianyun Wang, Daohao Tang, Cuizhu Wang, Fang Wang, Pingya Li, Jinping Liu
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2023.155292
影响因子：7.9
引用产品： Caco-2 细胞
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Diterpenoid honatisine overcomes temozolomide resistance in glioblastoma by inducing mitonuclear protein imbalance through disruption of TFAM-mediated mtDNA transcription(2023)
作者：Zongyang Li, Ke Sai, Guoxu Ma, Fanfan Chen, Xudong Xu, Lei Chen, Sicen Wang, Weiping Li, Guodong Huang, Ping Cui
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2023.155328
影响因子：7.9
引用产品： SK-OV-3 细胞, Caco-2 细胞, PANC-1 细胞, PC-3 细胞, NCI-H1395 细胞, MCF7 [MCF-7] 细胞
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Chlorogenic acid regulates the expression of NPC1L1 and HMGCR through PXR and SREBP2 signaling pathways and their interactions with HSP90 to maintain cholesterol homeostasis(2023)
作者：Chao Meng, Lingye Zhou, Lin Huang, Qi Gu, Xinyue Du, Cheng Wang, Fanglan Liu, Chunhua Xia
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2023.155271
影响因子：7.9
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SKN-1/NRF2 upregulation by vitamin A is conserved from nematodes to mammals and is critical for lifespan extension in Caenorhabditis elegans(2023)
作者：Chaweewan Sirakawin, Dongfa Lin, Ziyue Zhou, Xiaoxin Wang, Rhianne Kelleher, Shangyuan Huang, Weimiao Long, Andre Pires-daSilva, Yu Liu, Jingjing Wang, Ilya A. Vinnikov
期刊：AGING CELL
影响因子：7.8
引用产品： IMR-90 细胞, Caco-2 细胞
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Q1:为什么我看的文献里的细胞培养条件和你们官网的培养条件不一样呢？
部分细胞是会出现多种培养条件的，我们公司优先选择引种来源的培养条件以及建系者所用培养条件，出现差异的原因是不同实验室在保藏过程中更改了细胞的培养条件，为了避免细胞突然更换培养条件后不适应，建议您优先使用厂家推荐的培养条件培养。
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