货号： CL-0050
Price： ￥1600 ￥1600
生长培养基： MEM（含NEAA）[PM150410]+20%FBS[164210]+1%P/S[PB180120]
产品信息
| 产品名称 | Caco-2（人结直肠腺癌细胞） |
| 别称 | CaCo-2; CACO-2; Caco 2; CACO 2; CACO2; CaCo2; CaCO2; Caco2; Caco-2/ATCC |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 |
冻存液：55% 基础培养基+40% FBS+5% DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:MEM（含NEAA）[PM150410]+20%FBS[164210]+1%P/S[PB180120] 培养条件: 气相：空气，95%；CO₂，5%, 温度：37℃ |
| 培养方案B（可选） |
生长培养基: 培养条件: 气相：, 温度：37℃ |
| 推荐传代比例 | 1:3-1:6 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 |
|
参考资料(来源文献)
| 背景描述 | Caco-2细胞分离自直肠原位癌；当长到满时，Caco-2细胞表现出特征性的肠上皮细胞分化。Caco-2细胞表达维甲酸结合蛋白I和维甲酸结合蛋白Ⅱ，并呈角质蛋白阳性。 |
| 年龄（性别） | 72Y Male |
| 组织来源 | 结肠，结直肠腺癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肠癌细胞 |
| 生物安全等级 | BSL-1 |
| 致瘤性 | Yes, in nude mice; forms moderately well differentiated adenocarcinoma consistent with colonic primary (grade II). |
| 受体表达情况 | This cell line expressed heat stable enterotoxin (Sta, E. coli) and epidermal growth factor (EGF). |
STR位点信息
STR鉴定图
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Novel Applications of Yinhua Miyanling Tablets in Ulcerative Colitis Treatment Based on Metabolomics and Network Pharmacology(2024)
作者：Caixia Wang, Hui Yu, Zhuoqiao Li, Junzhe Wu, Peng Gao, Shanmei He, Daohao Tang, Qianyun Wang, Hanlin Liu, Haoming Lv, Jinping Liu
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2024.155366
影响因子：7.9
引用产品： Caco-2 细胞
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Enhancement of oral bioavailability of celastrol by chitosan microencapsulated porous starch carriers(2024)
作者：Jiangrui Wang, Xuewei Liang, Yan Du, Zhongjie Tang, Xuehui Duan, Zewei Sun, Jianquan Zhao, Wei Xu, Yingyi Wang, Yixuan Tang
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2024.137167
影响因子：7.7
引用产品： Caco-2 细胞
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Angiotensin converting enzyme (ACE) inhibitory peptide from the tuna (Thunnus thynnus) muscle: Screening, interaction mechanism and stability(2024)
作者：Shu Wang, Lu Zhang, Hui Wang, Jiaojiao Liu, Yueming Hu, Zongcai Tu
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2024.135469
影响因子：7.7
引用产品： Caco-2 细胞
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Tremella aurantialba polysaccharides alleviates ulcerative colitis in mice by improving intestinal barrier via modulating gut microbiota and inhibiting ferroptosis(2024)
作者：Gong Peng, Sisi Wang, Hansi Zhang, Fang Xie, Li Jiao, Ye Yuan, Cheng Ma, Hui Wu, Zhaoli Meng
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2024.135835
影响因子：7.7
引用产品： Caco-2 细胞
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Sestrin2 reduces ferroptosis via the Keap1/Nrf2 signaling pathway after intestinal ischemia-reperfusion(2024)
作者：Le-le Zhang, Ke Ding, Shi-shi Liao, Yi-guo Zhang, Hui-yang Liao, Rong Chen, Qing-tao Meng
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2024.02.003
影响因子：7.4
引用产品： Caco-2 细胞, 特级胎牛血清, 青霉素-链霉素溶液 (双抗)，100×
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MCU inhibition protects against intestinal ischemia?reperfusion by inhibiting Drp1-dependent mitochondrial fission(2024)
作者：Tulanisa Kadier, Yi-guo Zhang, Yi-xin Jing, Zi-yi Weng, Shi-shi Liao, Jie Luo, Ke Ding, Chen Cao, Rong Chen, Qing-tao Meng
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2024.05.024
影响因子：7.4
引用产品： Caco-2 细胞
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Self-Adhesive, Anti-Freezing Multifunctional Zwitterionic Hydrogels with Lignin-Promoted Rapid Gelation for Flexible Strain Sensors(2024)
作者：Yutong He, Shaochao Sun, Xinxu Zhang, Ying Xu, Chen Zhang, Changyou Shao, Jun Yang, Jialong Wen
期刊：ACS Sustainable Chemistry & Engineering
DOI：10.1021/acssuschemeng.4c04344
影响因子：7.1
引用产品： HL-7702 [L-02; LO2] 细胞, Caco-2 细胞
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Oleanolic acid 28-O-β-D-glucopyranoside: A novel therapeutic agent against ulcerative colitis via anti-inflammatory, barrier-preservation, and gut microbiota-modulation(2024)
作者：Caixia Wang, Hanlin Liu, Zhuoqiao Li, Qingya Yang, Qianyun Wang, Ting Yang, Daohao Tang, Cuizhu Wang, Jinping Liu
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2024.117534
影响因子：6.9
引用产品： Caco-2 细胞
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Single-cell calcium monitoring of Caco-2?cell co-cultured with intestinal microbiome through carbon fiber based potentiometric microelectrode(2024)
作者：Jiali Zhai, Zhedong Qiu, Yushan Liu, Yahui Niu, Ronghua Chen, Xiaomeng Kao, Wencheng Dong, Lijuan Kou, Guangtao Zhao
期刊：ANALYTICA CHIMICA ACTA
影响因子：6.2
引用产品： Caco-2 细胞
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A branched galactoglucan from Lysimachia christinae: Structural characterization, immunoregulatory and anti-oxidant bioactivities in vitro and in vivo(2024)
作者：Yong-Fei Zhou, Jiaojiao Nie, Ji-Xiang Sun, Weiwei Zheng, Chao Shi, Ke Ning, Mingshuo Ji, Qiuhong Xie, Hongyu Xiang
期刊：Carbohydrate Polymer Technologies and Applications
DOI：10.1016/j.carpta.2024.100653
影响因子：6.2
引用产品： HL-7702 [L-02; LO2] 细胞, Hepa 1-6 细胞, Caco-2 细胞
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Q1:为什么我看的文献里的细胞培养条件和你们官网的培养条件不一样呢？
部分细胞是会出现多种培养条件的，我们公司优先选择引种来源的培养条件以及建系者所用培养条件，出现差异的原因是不同实验室在保藏过程中更改了细胞的培养条件，为了避免细胞突然更换培养条件后不适应，建议您优先使用厂家推荐的培养条件培养。
识别码示意图
