货号: CL-0603
Price: ¥2200 ¥2200
生长培养基: DMEM/F12[PM150312]+10% FBS[164210]+1% P/S[PB180120]
产品信息
产品名称 | KGN(人卵巢颗粒细胞) |
生长特性 | 贴壁细胞 |
细胞形态 | 成纤维细胞样 |
冻存条件 |
冻存液:55% 基础培养基+40% FBS+5% DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:DMEM/F12[PM150312]+10% FBS[164210]+1% P/S[PB180120] 培养条件: 气相:空气,95%;CO₂,5%, 温度:37℃ |
培养方案B(可选) |
生长培养基: 培养条件: 气相:, 温度:37℃ |
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
参考资料(来源文献)
背景描述 | Granulosa cell tumor. Possible to produce progesterone after HCG addition. Cell growth is slow. |
年龄(性别) | 69Y Female |
组织来源 | 卵巢,腹膜 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 卵巢癌细胞 |
生物安全等级 | BSL-1 |
STR位点信息
STR鉴定图
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Excessive fluoride induces ovarian function impairment by regulating levels of ferroptosis in fluorosis women and ovarian granulosa cells(2024)
作者:Nan Geng, Siyuan Dong, Pengpeng Xie, Yi Zhang, Rong Shi, Chen Chen, Zhao Xu, Qun Chen
期刊:REPRODUCTIVE TOXICOLOGY
DOI:10.1016/j.reprotox.2024.108556
影响因子:3.3
引用产品: KGN 细胞
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Potential mechanism prediction of indole-3-propionic acid against diminished ovarian reserve via network pharmacology, molecular docking and experimental verification(2024)
作者:Liu Ahui, Liu Zhijun, Shen Haofei, Du Wenjing, Jiang Yanbiao, Wang Liyan, Zhang Rui, Jin Panpan, Zhang Xuehong
期刊:BMC Complementary Medicine and Therapies
DOI:10.1186/s12906-024-04611-1
影响因子:3.3
引用产品: KGN 细胞
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The melatonin-FTO-ATF4 signaling pathway protects granulosa cells from cisplatin-induced chemotherapeutic toxicity by suppressing ferroptosis(2024)
作者:Wang Rongli, Geng Jing
期刊:JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
DOI:10.1007/s10815-024-03276-6
影响因子:3.2
引用产品: KGN 细胞
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SOX4 regulates proliferation and apoptosis of human ovarian granulosa-like tumor cell line KGN through the Hippo pathway(2024)
作者:Qiang Hong, Mengmeng Fan, Rui Cai, Wenhui Shi, Fenfen Xie, Yuanhua Chen, Cong Li
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2024.149738
影响因子:3.1
引用产品: KGN 细胞
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Nuciferine protects hyperandrogen-injured ovarian granulosa cells by inhibiting ferroptosis via SOX2-mediated activation of the SLC7A11/GPX4 axis(2024)
作者:Hongyu Yang, Shichao Chen, Shanshan Yin, Qi Ding
期刊:JOURNAL OF APPLIED TOXICOLOGY
DOI:10.1002/jat.4697
影响因子:2.7
引用产品: KGN 细胞
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NOX4 deficiency improves the impaired viability, inhibited the apoptosis and suppressed autophagy of DHEA-treated ovarian granulosa cells through inhibiting endoplasmic reticulum stress via inactivating PERK/ATF4 pathway(2024)
作者:Na Yu, Lingyuan Wu, Xin Xing
期刊:TISSUE & CELL
DOI:10.1016/j.tice.2024.102640
影响因子:2.7
引用产品: KGN 细胞
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Menstrual Blood-Derived Endometrial Stem Cells Ameliorate Ovarian Senescence by Relieving Oxidative Stress-Induced Inflammation(2024)
作者:Song Haofeng, Zhang Ruiyun, Liu Yinglei, Wu Jie, Fan Wenqiang, Wu Junfang, Liu Yanli, Lin Juntang
期刊:Reproductive Sciences
DOI:10.1007/s43032-024-01739-w
影响因子:2.6
引用产品: KGN 细胞
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Naringenin mitigates cadmium-induced cell death, oxidative stress, mitochondrial dysfunction, and inflammation in KGN cells by regulating the expression of sirtuin-1(2024)
作者:Ben Yuan, Junbiao Mao, Junling Wang, Shuhong Luo, Bingbing Luo
期刊:DRUG AND CHEMICAL TOXICOLOGY
DOI:10.1080/01480545.2023.2288798
影响因子:2.6
引用产品: KGN 细胞
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Circ_0043314 modulates proliferation and apoptosis of ovarian granulosa cells in polycystic ovarian syndrome via the microRNA-146b-3p/Apelin 13 axis(2024)
作者:Wang Wei, Tan Luni, Ge Liang, Gou Ruiqiang, Gou Li, Liu Lin, Zhang Lili, Ma Xiaoling
期刊:GYNECOLOGIC AND OBSTETRIC INVESTIGATION
影响因子:2.0
引用产品: 293T [HEK-293T] 细胞, KGN 细胞
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Lycopene mitigates DHT-induced apoptosis and oxidative stress in human granulosa cell line KGN by regulating the Nrf2 pathway(2024)
作者:Chen Yue, Zhao Mengmeng, Li Xiaoqing, Liu Yuanyuan, Shang Yuhong
期刊:Molecular & Cellular Toxicology
DOI:10.1007/s13273-023-00419-1
影响因子:1.7
引用产品: KGN 细胞
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Q1:为什么我看的文献里的细胞培养条件和你们官网的培养条件不一样呢?
部分细胞是会出现多种培养条件的,我们公司优先选择引种来源的培养条件以及建系者所用培养条件,出现差异的原因是不同实验室在保藏过程中更改了细胞的培养条件,为了避免细胞突然更换培养条件后不适应,建议您优先使用厂家推荐的培养条件培养。

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