货号： CL-0265
Price： ￥1600 ￥1600
生长培养基： DMEM[PM150210]+10% FBS[164210]+1% P/S[PB180120]
产品信息
| 产品名称 | CAL 27（人舌鳞癌细胞） |
| 别称 | Cal-27; CAL 27; Cal 27; CAL27; Cal27; Centre Antoine Lacassagne-27 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 |
冻存液：55% 基础培养基+40% FBS+5% DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:DMEM[PM150210]+10% FBS[164210]+1% P/S[PB180120] 培养条件: 气相：空气，95%；CO₂，5%, 温度：37℃ |
| 培养方案B（可选） |
生长培养基: 培养条件: 气相：, 温度：37℃ |
| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
参考资料(来源文献)
| 背景描述 | CAL 27细胞是由J·Gioanni于1982年建系，源自一位56岁白人男性的舌头中倍的病变部位；CAL 27细胞角蛋白强阳性。 |
| 年龄（性别） | 56Y Male |
| 组织来源 | 舌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 舌鳞癌细胞 |
| 生物安全等级 | BSL-1 |
| 致瘤性 | Yes, solid tumors developed within 6 weeks in nude mice inoculated with 2×10<sup>6</sup> cells subcutaneously. |
STR位点信息
STR鉴定图
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USP14 promotes the cancer stem-like cell properties of OSCC via promoting SOX2 deubiquitination(2024)
作者：Chang Liu, Shijie Zhou, Wei Tang
期刊：ORAL DISEASES
影响因子：3.8
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Cancer-associated fibroblast-derived extracellular vesicles promote lymph node metastases in oral cavity squamous cell carcinoma by encapsulating ITGB1 and BMI1(2024)
作者：Lv Tianzhu, Liu Hongjing, Mao Ling, Song Yanrong, Liao Lili, Zhong Kun, Shuai Binbin, Luo Yingkun, Guo Tingting, Huang Wentao, Zhang Shenyingjie
期刊：BMC CANCER
DOI：10.1186/s12885-024-11855-0
影响因子：3.8
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CLSPN actives Wnt/β-catenin signaling to facilitate glycolysis and cell proliferation in oral squamous cell carcinoma(2024)
作者：Zeyu Hou, Chenzhou Wu, Jinru Tang, Longjiang Li, Shaohua Liu
期刊：EXPERIMENTAL CELL RESEARCH
DOI：10.1016/j.yexcr.2024.113935
影响因子：3.7
引用产品： SCC-9 [SCC 9; SCC9] 细胞, TSCCa 细胞, CAL 27 细胞, DMEM/F12完全培养基 (含10%FBS）
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Dihydroartemisinin inhibits HNSCC invasion and migration by controlling miR-195-5p expression(2024)
作者：Xiaolu Wu, Congwen Yang, Zhongwan Li, Ping Lv, Xiang An, Xiaohe Peng, You Li, Xiaojun Jiang, Xuemei Mao, Donghong Chen, Lifeng Jia, Wei Yuan
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e32522
影响因子：3.4
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Inhibin A contributes to the tumorigenesis of oral squamous cell carcinoma by KIAA1429-mediated m6A modification(2024)
作者：Xiaoqing Chen, Renxiu Fan
期刊：JOURNAL OF ORAL PATHOLOGY & MEDICINE
影响因子：3.3
引用产品： CAL 27 细胞, SCC-9 [SCC 9; SCC9] 细胞
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IFIT3 accelerates the progression of head and neck squamous cell carcinoma by targeting PD-L1 to activate PI3K/AKT signaling pathway(2024)
作者：Liu Peng, Kong Xin, Yi Shijiang, Chen Ying, Luo Wenlong
期刊：World Journal of Surgical Oncology
DOI：10.1186/s12957-023-03274-5
影响因子：3.2
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Isocorydine Exerts Anticancer Activity by Disrupting the Energy Metabolism and Filamentous Actin Structures of Oral Squamous Carcinoma Cells(2024)
作者：Qiaozhen Zhou, Qianqian Zhang, Lingzi Liao, Qian Li, Huidan Qu, Xinyu Wang, Ying Zhou, Guangzeng Zhang, Mingliang Sun, Kailiang Zhang, Baoping Zhang
期刊：CURRENT ISSUES IN MOLECULAR BIOLOGY
影响因子：3.1
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Synergistic inhibition of proliferation and induction of apoptosis in oral tongue squamous cell carcinoma by mebendazole and paclitaxel via PI3K/AKT pathway mitigation(2024)
作者：Zhang Jie, Cui Yanyan
期刊：NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
DOI：10.1007/s00210-024-03670-y
影响因子：3.1
引用产品： UM-SCC-1 细胞, 磷酸盐缓冲液（PBS） 1×, CAL 27 细胞, DMEM高糖 培养基
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Near-infrared imaging of head and neck squamous cell carcinoma using indocyanine green that targets the αvβ6 peptide(2024)
作者：Yuan Yuan, Tengfei Fan, Jingbo Wang, Ying Yuan, Xiaofeng Tao
期刊：JOURNAL OF BIOMEDICAL OPTICS
影响因子：3.0
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High expression of serine protease inhibitor kazal type 1 predicts poor prognosis and promotes the progression and invasion of oral tongue squamous cell carcinoma(2024)
作者：Shuang Wang, Yaping Sun, Dan Shao, Yunjie Pan, Xiaoyan Gao, Peng Zhao, Qiaoling Liu, Gaishuang Shang, Wei Shang, Zhiguang Fu, Yong Sun
期刊：ARCHIVES OF ORAL BIOLOGY
DOI：10.1016/j.archoralbio.2024.106003
影响因子：3.0
引用产品： CAL 27 细胞
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Q1:为什么我看的文献里的细胞培养条件和你们官网的培养条件不一样呢？
部分细胞是会出现多种培养条件的，我们公司优先选择引种来源的培养条件以及建系者所用培养条件，出现差异的原因是不同实验室在保藏过程中更改了细胞的培养条件，为了避免细胞突然更换培养条件后不适应，建议您优先使用厂家推荐的培养条件培养。
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